I have the Neo Hybrid and it isn't nearly as good as a tough case or Seidio cases I have had. Not sure I would recommend it, nothing particularly wrong with it but it lacks the cushioning of a touch case, dilex, commuter, etc which in my experience is a major help in drops. It also lacks their better grip and feel in hand. Best thing that can be said for it is that it doesn't look cheap and it will keep the phone from getting scratched. I had a toughcase on my sgs 2, 3, and 4 and obviously between the phones over the course of years there were a number of drops but never a break. Out of those the otterbox boys claim there will be no commuter for the N5, casemate is still mum but does have one case for it coming soon and there may be hope for the tough case and seidio is just now getting there cases on the market. Myself I have a dilex coming Monday which should prove better than the Neo I have now and if Casemate gets the toughcase out I'll buy that in a heartbeat. Easily the best I have ever owned and I have been through a number of cases looking for a better mouse trap over the years. Otterbox quality seems to have gone down over the last few years and their commuter is bested by the tough case anyways making them a poor choice even if they did make one. Seidio I haven't had in a few years so for me the jury is out on them till I try the one I have coming now. Previous cases I had with them were good however.
None of these would help you though if you want screen protection. The only real way to do that is a pouch or a wallet style. Those have their own issues.. The pouch is great when the phone is in it but does nothing when its not and you tend to drop the phone when you're using it, not when its in its pouch in your pocket. Also its another thing in between you and answering a call. Wallets have the advantage of being on the phone when it falls but these can be among the thickest of the cases and some people hate having to fold the flap over to use the phone. I'm one of those, the protection is great but I find them too annoying in use. This is something you have to try for yourself to see where you stand.
In the end no case is perfect, each style has its compromise and you are going to have to choose which ones you want to make personally because you cant have it all in one case.