Yes, it's possible.
You have to do all the steps of rooting till you'll reach "recovery" mode (just before wipe and flash).
than just run the debugger
Code:
./adb shell
withing the shell

Code:
mount /system
list your apps with:
Code:
ls /system/app
now you can delete app:

Code:
rm /system/app/FriendStream*
and so on

It's good idea to backup your apps on sdcard

Code:
mount /sdcard
mkdir /sdcard/backup
cp /system/app/* /sdcard/backup
after work is finished

Code:
umount /sdcard
umount /system
reboot and you're done

It's good idea to wipe data after removing apps to avoid some junk in app manager.
MJ | Nexus 4; HTC One S; Nexus S; Lumia 820; iPhone 5