Stock ICS lags like hell, and while it may be true that every build is getting smoother, it still has its issues. But given the fact folks are working without a source for DHD, it's ok. It's coming along pretty good.
As for Sense 4.0, the One V RUU should be a good base for DHD, but then again, being a new phone with hardware changes, I wouldn't expect much.
If my post has been helpful or if you think I'm a jerk because I'm painfully honest.... Hit THANKS. It doesn't hurt.