I've been using ADW EX on my phone since Droid, so I naturally just started using it on the tablet/ It works great for me. It just has a little learning curve until you have everything setup like you want. Then just back it up and if you do a reset you can restore everything back.
Another little app I like is Folder Editor. It gives you choices on the type of folder to use and either light or dark, and it's easy to add apps to the folder.
I like to have folders on one desktop for different areas of study. Science, Survival, Radio, Navigation, System, etc. with the apps pertaining to those areas in those folders for quick access.