Default [Q] Omni ROM- safe for production on Nexus5 or S4mini?

Relatively new to the whole world of custom ROMs on Android devices. I've successfully rooted my Nexus5 since I am developing custom software that must integrate with bluetooth. I've read a bit about custom ROMs and was wondering if it was generally considered NOT a best practice to use any sort of custom mod(kernel, ROM) in a production environment.

Or are there some mods that are 100% reliable?