Originally Posted by AceofSpades117
Does this mean I don't have to root? And do I need to do anything with S-off or S-on?
Also, since I'm planning on flashing the ROM as soon as I get the phone (meaning there will be no apps that didn't come with the phone and the settings will stay default) do I even need to backup with Titanium?
your custom rom will be 'rooted', so no, there's nothing extra to do.
the nandroid backup you take is like a snapshot of your stock rom. can be handy if you ever need to go back to stock for repair etc.
in the circumstances you provided, I probably wouldn't backup the stock apps with Titanium, but there might be some carrier specific stuff you want to keep.
most roms don't need s-off. check and see in the individual rom threads, so s-off is not a mandatory thing to do.
HTC M7 (One)
ROM: ViperOne 5.7.0