Default [Q] N00B S-Off/Unlock Root questions

I have been around Android since the OG droid and have rooted all of my phones, but S-Off is new to me. I understand that S-Off allows everything else (unlock/root). I also know that historically when you are rooted you don't want to take OTA updates.

My questions are:
  • Does S-Off prevent you from taking OTAs?
  • Can OTAs change S-Off status?
  • Are there any self-contained resources explaining S-Off that I could read to be less dumb about it?