Nova Prime user for last year or so.. Used TW for few days to try it out but couldn't wait to get back to Nova just for all the customization options I use 7x5 home screen and app drawer grids, 6 icons on dock instead of 4, custom gestures, and it's nice to be able to backup and restore home screen setup after flashing new ROMS..
My personal opinion yours will vary..
Nova Prime>Apex>Google Now Launcher>Sense>TouchWiz
Sprint G900P -
MOAR & KT or R.D.D.T & The Governaa'
► † ONE (M7) ► † EVO 3D ► † EVO 4G ► † Touch Pro2 ► † Touch Pro ►