I know that android is designed to ballance apps in the background on the fly, but when your main use it to use just the one app, would playing with the "limit background processes", "force gpu rendering" and other options I perhaps have not considered help with the performance of the app in question (even if its at the cost of having a slower tablet in general due to having to load up processes on the fly rather than having them stored in RAM)?
Would this also help with resource intensive games?
I already turn all the animation options off, have a plain background and limit the number of widgets on my homescreens in order to free up as much as possible for my art apps in question.
I also use Greenify to limit apps opening on their own accord and use a gaming booster than shuts down other background apps and stops them opening when said art apps are in use.
I used to OC, but have gone back to 1600mhz and 533mhz for the CPU and GPU respectively having had concerns with how hot my tablet gets in the edge of the screen under load.