I went with Nova, because it will keep me from going insane until I can flash an AOSP ROM. Kept things simple, mostly bookmarks and website apps. For social networking, I use the Twitter/FB/G+ widgets which are all on the far left screen. News feed and calender goes to the left of the main screen. Games, settings widgets, and contact shortcuts go on the right. Because I use so many rows and columns, my far right screen can stay empty.
I usually create my own wallpaper (as a graphic designer, I have a compulsion to customize everything), but I actually really like the wallpaper here, which is one of the HTC included ones. I might keep it.