Hi there...I was directed here from the transformerforums.com to ask about this issue. I have a B50-vintage TF101 with keyboard dock. Since the 2nd ICS update, my Transformer has developed the annoying habit of the screen randomly popping on for no reason. I know on that other site there were users seeing this happen, but I tried my best to search here and didn't see it in the search (at least not for the Transformer).
So, I did some playing around and noticed a few things. The annoying "screen coming on for no reason" issue happens only when the tablet is docked in the keyboard. The screen will come on for 10 seconds and then go off again (my default screen timeout is 5 minutes). It is almost as though some kind of notification is coming in, waking up the tablet for a moment.
I believe the issue is the "Charged" notification. I did the following experiment several times: I undocked the tablet, allowed it to discharge to about 95%. Then I plugged it back into the keyboard dock, and waited. The tablet goes into "charging" mode (with the little bolt icon on the battery). If I hit the lock button and wait, the screen goes off and stays off..it does not randomly pop back on again. Not until "Charged" has been hit. After that, the screen randomly comes on again as before.
Further, I noticed that whenever it comes on, it activates WiFi as well. I have my WiFi set to only come on when I am using the tablet. This explains the tablet waking me up in the middle of the night with new email notifications.
Not sure if this helps any...it seems reproducable to me, and definitely a regression (especially from Honeycomb).