Software issues I consider somewhat silly since they'll most likely be fixed in the future (although to be fair, Google shouldn't even allow RMA on software issues that "can" be fixed over time). Hardware issues in the other hand vary between devices....Is anyone else shocked by the sheer number of people that will happily request multiple replacements because of the stupidest things and then wonder why the price increases or the customer service seems rushed? They've somehow got pay for all the testing, repackaging, restocking and reselling of these apparently 'defective' devices.
I don't consider $400+ "pocket change" and I'd want the best device I could get for my money. a creaky back and noticeable light bleed are things I would not even want to be bothered with on such a priced device, and if I really want the device, i'd try multiple times to get a decent one.
My first Nexus 10 has no dead pixels, no creaky back, and very minimal light bleed. This device is fine for me, but ideally I wouldn't even want the light bleed. I'm not going to RMA over it now, but I didn't do it in the past either at the risk of getting a worse tablet (it's real bad that this is even a concern sadly). Samsung's RMA might be a better option since they actually repair the device (not sure how good of a job they do) but it can take weeks, and Samsung doesn't even seem to know their tablet exists most of the time.
If Google and Samsung don't want to deal with a lot of RMA's, then they should make their quality check process better.