Assuming:
- Your current build is the AT&T Stock I337UCUAMDL
- You have not uninstalled any bloatware (freezing/disabling is OK)
- You haven't modified any system files that might be otherwise be used by the MF3 patch
... then you should be good-to-go by starting with Step 13 - Flashing the MF3-Neutered.zip.
- You might need to wipe data, but you are welcome to try it without wiping. At least wipe your cache/dalvik. If you run into a lot of force-closes, you'll need to wipe data too.
- You should still flash UPDATE-SuperSU-v1.41.zip to root your new MF3 build, at the least. You can also flash the other patches as you need.
In a nutshell: you might be able to get away with it. If you want JUST the modem update, you can update just that int he bottom section of the OP. In any event, be sure to take a full nandroid backup first, so that you can easily revert back.
Good luck.