This thread sums up our pool of knowledge, spread over a couple of threads and condensed into one.
We were bouncing back and forth between freezing and uninstalling, in various configurations right after we got root, and I re-wrote everything into posts 19 through 25.
You can pick and choose what you want to get rid of - the only apps that have a dependency on something else are:
-The two "my account" apps, which is explained in the thread and:
-Widgets after removing the Sense launcher.
Removing the Sense launcher (rosie.apk) means you can't use a majority of the pre-installed widgets that come on the phone. It's safe to remove any and all widgets without affecting the apps they link to, whether you remove the Sense launcher or not.
In that thread I linked, we do not cover removing any of the Sense frameworks or deep system files, just surface .apks - so it's all pretty safe there. The stock camera app will still function, as well as anything else that depends on Sense frameworks to run correctly.
You can pick and choose what you want to get rid of in the list - and it's very specifically listed where the .apk and /data files are located so you can make sure everything got removed ok.
I would recommend using
Absolute System Root Tools to uninstall the apps, and make sure to clear the data first.
Go back afterwards and use
Root Explorer to delete the empty data folders left behind, and the .odex files that Absolute system (or any other uninstaller) won't get rid of.
Again, all the paths and full names of the .apk and .odex files, as well as the /data folders are listed explicitly in the thread, so you should have no trouble finding everything for each specific app you want to get rid of.
It was a big effort from quite a few people here to track it all down, and we are still adding more stuff to the list. If you find something you can get rid of that we haven't covered, add it to the thread so others don't have to re-invent the wheel.
Happy hunting!
Edit -*(you can use Absolute System to remove those folders and files left behind with the root system file browser I believe, but I prefer root explorer and if you're gonna do this kind of stuff you should pick it up anyway - it's worth the money)
I have no experience with titanium backup, but if you can do all the functions of that with it, then more power to you, post up here if you can use that to delete the empty folders and .odex files that it probably won't get.