Things like this have been done before. Search Android Phone 7. I've never seen one with that app list sidebar. That may be a little hard to recreate but it isn't impossible.
Things you'd need: Icons, Desktop Visualizer, ADW EX or Launcher Pro Plus (Plus is needed for resizing widgets) Minimalistic Text, maybe Phantom Music Control. For the icons like "Games" or "Utilities" you may be able to link the DVR widget to an app called Folder Organizator. Or you could use a widget called SiMi Folder, which would make a shortcut on your homescreen that is like the iPhone's folder thing. You could make the icon of the SiMi Folder transparent.
This is going to take A LOT of resizing, which can get really boring. To avoid headaches, plan everything out before you start. If you want a widget above another widget, the widget you want on the bottom (background) needs to be placed BEFORE the widget you want in front (foreground). You are going to have to resize it over the other widget, not place it on top.
That's all I can think of for right now. The left side should be pretty easy. The right side on the other hand will be a little challenging. My best advice would be to start by making a big plain minimalistic text (MT) widget, then add each app name as a MT widget with a blank background (option is in the MT widget configuration menu) For some help, try the Hubs layout in the Asus Transformer Theme and App section. We have a nice thread there with a similar idea and people there will be more than willing to help. They are a lot better at home screen customization than me.
Anyways, awesome idea! If you make the icons, I'll be happy to help you recreate it!