the screen doesnt take long at all to get used to plus the support for the one-x will be very long term indeed on this forum.
one of the devs has made a swipe to wake function (basically slide your finger right on the three soft keys to wake the phone!) which should stop having to reach for the power button all the time.
Having said that, my missus has the one-s and its a bloody sweet phone i must say but will sill say go one-x
Really sharp screen, can run tegra games, awesome camera, just for starters!