This thread is dedicated to SuperSU on N Preview. With the first few releases I'm not merging it directly with the BETA branch, as there have been some invasive changes under the hood regarding SELinux handling, and there should be a little bit more testing done before going there. Still, I expect this to be done within the next week or two.
I've only had the chance to test on the 5X so far, so there is some risk involved. If you're not comfortable reflashing everything due to bootloops, crashes, etc, wait for others to play the guinea pig.
As this hasn't been merged with the BETA branch yet, I'm not updating the main CF-Auto-Root distribution either. But as TWRP isn't working yet on all N Preview devices either, attached are test CFAR versions.
Note that you are also welcome to flash this SuperSU version on pre-N firmwares, and report back if everything still works as expected.
If you have tried other methods of rooting, you need to at least flash back your stock boot.img before flashing SuperSU.
Depending on how much you have played around, reflashing /system may also be a wise move.
If you came from SuperSU v2.69, you need to reflash via TWRP or CFAR. Installing just the APK and updating binaries will not fix all the issues!