After a few days of use, I realize what a good decision it was to move the power button. I am right handed but hold phone in my left hand.
I felt the same about the fp sensor so I am using face unlock now and surprised how fast it works.
I am getting close to 7 hours of SoT which is about 1.5 - 2 hours more for me than the Note9.
Not sure if I can suggest anything for battery issue. I was getting the same before I debloated as I am getting now after debloating. However, this time around on Note10+ I got rid of a lot of Google apps and using MS apps instead. I know Chrome use to eat more battery than the Samsung Browser or IE and I started to get a lot of notifications about Maps using a lot of background battery.