There are a few things I have been able to access in Kaiser tweak that are not in adv cfg. I can't remember them offhand, but I do remember at least one or two or settings I normally change first. Kaiser tweak's UI isn't as "pretty" as adv cfg, but I have found it more useful for myself.
FWIW, there are also some items in adv cfg, via the right soft button IIRC, that aren't in Kaiser tweak. I never used those anyway, so it wasn't an issue for me.
Just install them both and decide for yourself which you need, or keep them both in. They are both small files. Your needs will vary, I'm sure.