Another solution: I use Phone Weaver (SBSH) - SPB makes equivalent Phone Suite, but I like Weaver better...
My setup = My phone not only goes to vibrate mode whenever certain categorized appts happen in my calendar (meetings/Clients/gigs), but every night at midnight it turns to silent or vibrate, the push mail shuts off, bluetooth shuts off if its on. At 5 am, wifi turns on and SPB backup kicks in if AC plugged in and wirelessly backs up my whole phone to my desktop every day, then turns wifi off. Then in the morning, resume pushmail and volume full.
I rarely ever have to touch my volume settings unless im going to a movie or dinner or something. I never have to think about backing up/losing my backups on a lost/stolen storage card/phone.
I just checked G-Profile too cause I've never looked at it. It seems like it does mostly the same things as P Weaver. try all the trial versions, see what you like.