I've seen a lot of post here and other forums where people have broken their TF300 when trying to open up and change some broken hardware.
If you decide to open up your tablet for DIY repair. Allways do this first:
1. Before removing the back cover, remove any micro SD card and sim cards. Be careful with the audio and hdmi connector when when opening.
2. After removing the back cover: TURN THE SERVICE SWITCH OFF!!! This will power off the motherboard. After turning the service switch off, I strongly recomend also disconnecting the battery.
3. The copper shielding plate is the cooling for the CPU and graphics chips. Make sure to put it back excatly like it was if you remove it. There is also a little contact cooling paste that needs to be there. This is important to prevent overheating which could lead to instability issues or possibly premature hardware failure.
4. If your repair requires you to remove the LCD screeen. IT is EXTREMLY FRAGILE. Be very careful.
And at last a picture of where all the screws for the motherboard are located. Before starting a repair. Do the research and find out excatly what steps you need to do AND PUT EVERYTHING BACK TOGETHER EXACTLY LIKE IT WAS. Remember that every little screw and part where carefully put there by design of an engineer for a good reason.