I have never done the "wire trick". When I originally got my phone, it had the HBOOT 1.45.0007, I did S-OFF with Revolutionary, rooted, unlocked, and all was well. When the newer radio (11.59.3505.20_2) came out that also updated the HBOOT to 1.45.0013, I was told it would revert my phone to S-ON, but I don't think it did. It did update the HBOOT to 1.45.0013. I then had to relock the phone, go to HTCDEV and use the HTC unlock tool, then I re-rooted the phone. So, I've been HBOOT 1.45.0013, with radio 11.59.3504.20_2, and I'm S-OFF, unlocked, rooted, without ever doing a "wire trick".
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