Negative, I hadn't messed with any CPU settings. I just checked Venom Tweaks and Trickster mod, and my governor is set to Interactive. Overall, things have been much better since the second kernel update that @iHateWebOS posted for me to try.
Interestingly, twice in the last 2 days, I had the issue you mention where the touchscreen didn't work after waking the phone, I do have S2W and DT2W enabled, hmm. Never saw that before.
Speaking of which - iHateWebOS - I see you've since posted an even newer Sense kernel, should I also update to that one? In general, are your updated kernels built with FFC allowed by default?