Originally Posted by metal666fukhead
If you're talking about the downloadfile.apk, downloadfile1.apk files on your /sdcard/ yes.
If you're talking about the actual /cache folder off of the root, I'd still say yes. I was under the impression only the davlik and lost & found folders where there. Plus the cache folder can be wiped through the recovery menu without causing problems to the phone, it'll just take a while to boot up as it rebuilds the cache with the necessary files.
You could always copy them else where (using ADB, root explorer, estrongs, etc.). Erase them. If there's problems push them back