Just by testing the camera in different orientations (i.e., 180 degrees between pics) it seems like the brightness is not the same on both sides. While rotated 180 the bottom right corner exhibits the same slight blue tint as the initial top left corner.
Just don't use SA when shooting low light photos. It ramps up the ISO way too high that causes that and also over exposes a shot and blurs the photo because of too much noise. Try testing it in a moderately lit (artificial light) room and try SA, manual with different ISOs and Night Mode on scenes.
I did a 180 degree test earlier on Z3+ to make sure it's not a lens/sensor issue. Z5 does the same. You also need to make sure it's equally dark on both sides. Try it out. FYI, high/12800 ISO is not a bad thing. It's actually the best feature for shooting in 'low' light.
12800 ISO is not a bad thing, unless you're using a phone. Cameras on mobile, including the Z5, are just way too small compared to real cameras with large sensors and better hardware that just can't fit (yet) in a phone. Sony thought they would win the low-light mobile phone photography contest by introducing that insane high ISO, everyone else thought otherwise. It overexposes (way over) the shot and blurs everything to reduce too much noise. That's in the auto mode, which all tech review sites use in their reviews and that's why the Z5 (since the 12800 ISO was introduced in Z3) gets trashed in their comparison. At least you could still shoot a proper low-light photo using the manual controls by controlling the exposure and ISO levels, or choosing night mode.