In my experiences trying to install OTA updates on my XT1644 using TWRP backups, yes--there was. Read this:Really? Was there a restore issue in version 3.1.1-0?
On most devices shipping with Android 6.0 or higher, the device maker has enabled dm-verity as a security measure. The device will signature check blocks of data on the system partition during boot at the block level. The usage of dm-verity prevents TWRP from being able to successfully restore a normal system backup. On most of these devices, you will see an option on the backup page for System Image. A system image backup takes up more space than a regular system backup, but the system image backup is a bit-perfect backup that, when restored, will not break dm-verity (assuming that you don't break dm-verity before making the backup).