I could not get 4.0 factory to work so I have been using the 4.0 and selecting other in the drop down and it's worked great for me . Hth
I've been getting this same "The system cannot find the file specified" problem from Device Manager and FINALLY figured out how to get up-to-date Windows 10 to work!!
Assuming the device is already plugged into the computer in EDL mode:
After the prompt gets the error from trying to load the cab file it will offer to search Windows Update to find a driver. After one or two of saying "Yes, please search" in Device Manager it will open the Windows Update section of Windows Settings and there's a little "Optional Updates" section that's collapsed. If you go to it, it offers this driver:
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Check the box for the driver, allow Windows Update to install it, then Device Manager should properly have the Qualcomm device under Ports instead of Other Devices. MSM should now recognize the device and be able to flash it!
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I finally have my device working again!!
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your a god that walks among us mortals! LOL