[Q] Safe to use 4.2.1 based custom ROM's after upgrading to 4.2.2?

[NoSauce]

If I don't like the stock 4.2.2 and want to go back to a 4.2.1 based custom ROM is it cool to just wipe and install them (per usual)? One would imagine it'd be fine since I'll be wiping everything but want to make sure. I'm not sure if there's some kind of firmware component of 4.2.2 that'll render my Nexus 7 incompatible with the 4.2.1 custom ROMs out there.

If it's not okay is it possible to downgrade back down to 4.2.1 from a factory image and then install these custom ROM's?

Thanks ahead of time.