I was looking for a thread for USB experiences on the Z4 tablet and found this. At the same time, I've been experimenting with different setups and also testing the problems cited here. I've had NO problems so far, so I'll give a run down on what I've been running.
I have a USB non-powered hub attached. From that, I'm running wireless keyboard/mouse combo. At the same time, I've attached a powered external Maxell HDD, which happens to be NTFS.
To mount the HDD, I've used ExFAT/NTFS. This opens directly into another required file management app called Total Commander (TC). ExFAT/NTFS needs to be running for the file commander app to access the HDD, but once it is, it appears in the list fine. I can also then switch between SD card browsing and HDD browsing in TC without any problems.
I also tested the concurrent running of apps via SD Card while the HDD is mounted. I moved Firefox over to the SD Card. When I did this, the transfer process unmounted the HDD in the background. So, I had to remount via ExFAT/NTFS, but once done, it ran again without problems. I then concurrently ran Firefox and Total Commander together, switching between the two and found NO problems. Again, I can also switch from the HDD to the SD Card without problems.
Assuming that this is the required level of concurrent use (browsing HDD and using SD Card mounted apps at the same time), then I'd say that Sony must have fixed the problems. There has been a major update to both the Sony UI and to Google's Nougat since this thread was active.
Just to add, I've had several keyboards and mice running at the same time via the one USB hub, without crashes, which was pleasing, though completely pointless
Will try to run some controllers via the USB next.