Give the app: ATP Tweak (version 7) a shot:
http://forum.xda-developers.com/showthread.php?t=1735887
(Download, then go down to the second post and make sure your app is set up the same way.)
I was having problems with The Amazing Spiderman and this helped.
If you are still having trouble, I would suggest the app: "Ram Manger Free/Pro" and select aggressive gaming option, and then the app: "AutoKiller Memory Optimizer" and hit memory reclaim until your Free Ram is above 500. I also noticed that setting my ASUS setting to powersaving mode helped (perhaps its placebo, but thats what i do before i play big games like, NOVA 3, Modern Combat 3, etc)
Goodluck