Crashes with MinMin Guard
I know that both xposed and MinMin Guard have very limited support (if any) on 5.1 thus far, but I figured I'd weigh in just in case anyone has a fix. On my setup, Cyanogenmod 12.1 with the super alpha xposed for 5.1, minmin guard installs and activates successfully, but any app that tries to load an ad immediately crashes, whether or not it's selected in minmin guard. Deactivating minmin guard in xposed installer makes the crashes stop.
UPDATE: SELinux is an important thing. I hadn't realized that Cyanogen 12.1 is set to enforcing rather than permssive. Once I set it to permissive, the module started working fine.